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The grand-nephew of pioneering physician Sir William Osler, Osler the actor was himself frequently cast as doctors or professors, in such Canadian films as Deadline (Dr. Masters), U-Turn (Professor Bamberger), and Something's Rotten (Dr. Conrad). As a voice actor, he was heard on the science-fiction series Starlost as the computer voice, and narrated episodes of the TV Ontario children's adventure series Read All About It (also shown on PBS).