In a 1998 Sesame Street episode, the agency recruits Slimey for a mission to the moon.  Staffed by a training officer and several highly trained worm technicians, they oversee the testing of a team of brave astronauts.
The roster includes Spaghettini from Italy, Squishta from Romania, Legusano from Colombia, Squashimi from Japan, Slogoshki from Poland, other worms from Puerto Rico and Zambia, and Selma Worm, who is actually a chicken dressed as a worm.
Five worms are ultimately chosen as the crew of the Wiggleprise. Their mission is administered from a control center based on Sesame Street, led by Professor Albert Einslime. It is this same crew of worms that can be seen in the recurring Worms in Space sketches.
Einslime and WASA returned to Sesame Street in 2007 to launch Slimey's girlfriend Glo Worm into space.  As before, worm technology couldn't sufficiently launch the rocket without some help from a Muppet; in this case the number 0, who saved the day by standing in for the final number of the count down.