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Talking Heads is a rock band featuring David Byrne, Chris Frantz, Tina Weymouth, and Jerry Harrison that disbanded in 1988.
- Their song "Wild Wild Life" was featured during a montage of clips in the Jim Henson Hour Pitch Reel.
- The Sesame Street song "Beginning, Middle, End" parodies their hit, "And She Was."
- Kermit the Frog performed their hit song "Once in a Lifetime" in episode 109 of Muppets Tonight. In the scene, Kermit wears a suit too large for him (it was made for the unseen guest performer Giganticus) that parodies the suit David Byrne wore on stage and in music videos.