SpongeBob SquarePants is an animated series that debuted on Nickelodeon in 1999 and soon became one of the channel's linchpin series. The title character appeared in the We Are Family music video alongside Muppet characters.
- In a 2004 promotional magazine for The SpongeBob SquarePants Movie, Patchy the Pirate hosts his own short section in which he names off the great movie pirates, including Tim Curry's performance as Long John Silver in Muppet Treasure Island.
- In It's a Very Merry Muppet Christmas Movie, while watching Kermit's flight on a video screen, the Boss tells Daniel he's "just lucky SpongeBob isn't on." Daniel soon tells her that he loves SpongeBob.
- Alec Baldwin voiced Dennis in The SpongeBob SquarePants Movie
- Tim Blaney played the Goofy Goober in The SpongeBob SquarePants Movie
- David Bowie voiced Lord Royal Highness in the episode "Atlantis SquarePantis"
- Tim Conway voices Barnacle Boy
- Bill Fagerbakke voices Patrick
- David Hasselhoff appeared as himself in The SpongeBob SquarePants Movie
- Ray Liotta voiced Bubble Poppin' Boys leader in the episode "WhoBob WhatPants?"
- Pat Morita played Master Udon in the episode "Karate Island"
- Brian Doyle-Murray played the Flying Dutchman in various episodes of the series
- John O'Hurley played King Neptune in two episodes; "Neptune's Spatula" and "The Clash of Triton"
- Patrick Pinney played Painty the Pirate, the buccaneer artwork who sings the series' theme song
- Gene Shalit played Gene Scallop in the episode "The Krusty Sponge"
- Jeffrey Tambor played King Neptune in The SpongeBob SquarePants Movie
- Frank Welker supplied voices in three episodes; "The Smoking Peanut", "My Pretty Seahorse", and "I Had an Accident"