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"She Blinded Me with Science" is a Thomas Dolby song which reached #5 on Billboard Magazine's Top 100 chart in 1983.
Dolby himself performed the song in the Ghost of Faffner Hall episode "Discovering New Sounds", accompanied by a Fly in a Matchbox.
Dr. Phil van Neuter performed the song in Muppets Tonight episode 104, in a flashback of how he met his enchanting wife, Composta Heap.