Scooby-Doo was a Hanna-Barbera animated series that was originally produced for Saturday morning television. Debuting in 1969 on CBS, the characters have appeared in numerous spin-offs and versions, as well as direct-to-video movies and prime-time specials. Beginning in 1998, Warner Bros. Animation took over production of the animated Scooby-Doo franchise.
The characters were brought to the big screen in a live-action adaptation in 2002, with Jim Henson's Creature Shop and David Barrington-Holt as Creative Supervisor/Character Design. The 2013 direct-to-video movie, Scooby Doo Adventures: The Mystery Map, features puppet versions of the characters operated by Muppet alumni, although it is not affiliated with the Jim Henson Company.
- When Josie and the Pussycats crossed over to The New Scooby-Doo Movies episode "The Haunted Showboat," Melody said of the vessel the gang was following into a cave, "He didn't even say, 'Open, Sesame Street'!"
- At the end of a Sesame Street Letter of the Day sketch for the letter Z, Prairie Dawn exclaims "Zoinks!", one of Shaggy's catchphrases in Scooby-Doo.
- The Merrill Lunch Hungerdunger McCormack All Accountant Marching Society finish their chant with a reference to Scooby-Doo.
- In The Muppet Show Comic Book: On the Road issue #4, when Kismet the Toad gets arrested, he says "I would have gotten away with it, too, if it weren't for you pesky pigs," referencing a line used whenever the villains on Scooby-Doo were caught.
- John Astin played Gomez Addams in The New Scooby-Doo Movies
- Rowan Atkinson played Emile Mondavarious in the 2002 live-action film
- David Beckham appeared in an Adidas advertisement in the UK with the Scooby-Doo gang (and also dressed up as Scooby-Doo in it)
- Mary Kay Bergman voiced Daphne in several Scooby-Doo videos
- Peter Boyle played "Old Man" Jeremiah Wickles in Scooby-Doo 2: Monsters Unleashed
- Daws Butler voiced Scooby-Dum
- JC Chasez was a guest star on A Scooby-Doo Valentine (and also dressed up as the titular dog in the same special)
- Cher was a guest star on The New Scooby-Doo Movies
- Mindy Cohn is the current voice of Velma Dinkley
- Tim Conway was a guest star on The New Scooby-Doo Movies
- Stephanie D'Abruzzo puppeteered and voiced Velma Dinkley on Scooby Doo! Adventures: The Mystery Map
- Phyllis Diller was a guest star on The New Scooby-Doo Movies
- Alice Dinnean puppeteered Daphne Blake and Dr. Escobar in Scooby-Doo! Adventures: The Mystery Map
- Sandy Duncan was a guest star on The New Scooby-Doo Movies
- Dick Van Dyke was a guest star on The New Scooby-Doo Movies
- Cass Elliot voiced herself in The New Scooby-Doo Movies
- Sholly Fisch has written several "Scooby Doo" comic books for DC Comics
- Paul McGinnis puppeteered in Scooby-Doo! Adventures: The Mystery Map
- Sarah Michelle Gellar played Daphne Blake in the first two live-action films
- Seth Green played Patrick Wisely in Scooby-Doo 2: Monsters Unleashed
- C. Ernst Harth played Miner 49er in Scooby-Doo 2: Monsters Unleashed, and the Janitor in Scooby-Doo! The Mystery Begins
- Eric Jacobson puppeteered as Shaggy Rogers in Scooby-Doo! Adventures: The Mystery Map
- Arte Johnson voiced Weerd in The 13 Ghosts of Scooby-Doo
- Casey Kasem voiced Shaggy on many Scooby-Doo productions from 1969 to 2010 and Colton Rogers on Scooby-Doo! Mystery Incorporated
- Don Knotts was a guest star on The New Scooby-Doo Movies
- Matthew Lillard played Shaggy Rogers in the first two live-action movies and has voiced him in projects since 2010
- Peter Linz puppeteered on Scooby Doo! Adventures: The Mystery Map, doing Ye Phantom Parrot, Gnarlybird, Stu, and Lighthouse Lou
- Mona Marshall did additional voices in Scooby-Doo and Scrappy-Doo
- Kellie Martin voiced Daphne in A Pup Named Scooby Doo
- Howard Morris voiced Bogel in The 13 Ghosts of Scooby-Doo
- Vincent Price voiced Vincent Van Ghoul in The 13 Ghosts of Scooby-Doo
- Geoff Redknap puppeteered on Scooby Doo 2: Monsters Unleashed
- Jerry Reed was a guest star on The New Scooby-Doo Movies
- David Rudman puppeteered Scooby-Doo on Scooby Doo! Adventures: The Mystery Map
- Adam Rudman puppeteered on Scooby Doo! Adventures: The Mystery Map
- Alicia Silverstone played Heather Jasper-Howe in Scooby-Doo 2: Monsters Unleashed
- John Stephenson voiced various villains in Scooby Doo
- Matt Vogel puppeteered Fred Jones in Scooby-Doo! Adventures: The Mystery Map
- Patrick Warburton voices Sheriff Stone on Scooby-Doo, Mystery Incorporated
- Frank Welker voiced Fred on Scooby-Doo, Where Are You! and its spinoffs, and is also the current voice of Scooby-Doo
- Jonathan Winters was a guest star on The New Scooby-Doo Movies