Quelle Difference is a French perfume sold at the Manhattan department store Bergdorf Goodman in The Muppets Take Manhattan. Miss Piggy and Eileen work at the perfume and cosmetics counter, and have trouble selling the fragrance.

As Piggy describes the perfume in a rage: "It's French! It's feminine! It'll help ya grab one of those rotten, stinkin' men!"

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