Neil Armstrong (1930-2012) was an astronaut, best remembered as the first person to set foot on the moon. He has been referenced by the Muppets on several occasions. His famous line upon landing was "That's one small step for [a] man, one giant leap for mankind."
- In a Sesame Street News Flash sketch, Natalie, the cow who jumped over the moon, paraphrases Armstrong: "A small jump for cow, a giant leap for cowdom!"
- The 1992 Dog City episode "Rocketship K-9" features a canine parody, Heel Arfstrong. He's the first dog on the moon: "One small step for a mutt, one giant leap for dogkind!"
- The 1997 coloring book Great Muppets in American History features Kermit as Armstrong landing on the moon.
- A 1998 episode of Sesame Street, as part of the "Slimey to the Moon" arc, features footage of Armstrong and Buzz Aldrin preparing for their famous flight.
- In the Star Wars-esque introduction for the 1999 rerun of episode 3740, Baby Bear describes Slimey's journey to the moon as "one small wiggle for a worm and one giant squiggle for worm-kind."
- Armstrong and John Glenn are cited by K. Edgar Singer in Muppets from Space as two historic figures with whom he'd be honored to be amongst as those Earthlings who have traveled in space.
- Big Bird and a child were inserted into footage of Armstrong and Aldrin planting the American flag on the moon for a 2000s PBS Interstitial.
- In Tales of a Sixth-Grade Muppet, when Danvers comes to school dressed in an astronaut costume, his best friend Pasquale states that after his previous bad day, "going to school dressed as Neil Armstrong isn't the best option."