Muhammad Ali (born Cassius Marcellus Clay Jr., 1942-2016) was an American boxer and an Olympic gold medal winner. Nicknamed "The Greatest", Ali was involved in several historic boxing matches, including those against rivals Joe Frazier and George Foreman. Sports Illustrated called Ali the "Sportsman of the Century".
- In a 1965 episode of The Jimmy Dean Show, Rowlf decides to take up boxing when he hears about the upcoming Cassius Clay and Floyd Patterson fight, with the winner of the match being challenged by Rowlf.
- In episode 323 of The Muppet Show, Kermit, dressed as Robin Hood tweaks one of Ali's oft quoted phrases, "I float like a butterfly, sting like a frog."
- Will Smith played Ali in the feature film Ali (2001)