Morgan De Sena is the daughter of Sesame Workshop talent coordinator, Danette De Sena.

De Sena appeared on Sesame Street as one of the kids throughout the 1990s. She appeared as early as Episode 2731 and made appearances in Episode 3121, Episode 3251, Episode 3444 and Episode 3656. She also appeared in the home video, Get Up and Dance.

Most notably, she appeared in some Muppet & Kid moments with Grover taped for season 24, helping him count, say the alphabet and show the parts of the body. She also portrayed Gabi in Episode 3101.