HBO (which stands for Home Box Office) is a premium cable television channel that specializes in showing movies, as well as original films and series. It is now owned by Time Warner.
Among the Henson productions that originally aired on HBO are Emmet Otter's Jug-Band Christmas (1977), Fraggle Rock, (1983-1987), The Tale of the Bunny Picnic (1986), and The Ghost of Faffner Hall (1989). Additionally, the Muppets appeared in the HBO special The Vent Event (1978). HBO has also aired The Muppet Movie, The Great Muppet Caper, The Muppets Take Manhattan, Muppet Treasure Island, Muppets from Space, Mr. Magorium's Wonder Emporium (containing Kermit's cameo) and Into the Night (containing Jim Henson's cameo).
In 1983, HBO held a Fraggle Rock Sweepstakes contest. The grand prize was a trip for a family of four to Fraggle Rock at Toronto's CBC Studios or New York City for the Macy's Thanksgiving Day Parade and a tour of The Muppet Workshop. Other prizes were a Fraggle Fun Pack which included a Fraggle Rock record and poster. A promo was filmed for this contest featuring Doc and Sprocket reading about the contest in a newspaper. Doc encouraged Sprocket to enter the contest so that they can figure out what a Fraggle is. Gobo Fraggle makes a silent appearance at the end as he overheard Doc's conversation. The contest ended on May 31, 1983.
- A 2010 episode of Sesame Street features "True Mud", a parody of HBO's original series, True Blood. Oscar the Grouch introduces the sketch, stating the program is shown on the station GrouchBO.
- The Moopets sing a version of "The Rainbow Connection" in The Muppets that features new lyrics that shills out for their casino. On the film's soundtrack, one of the new lyrics states that there's HBO in every room.