A list of Muppet and human grandmothers and grandfathers, both on screen and in books. In the case of long-running characters, the source listed is the character's first appearance.
- Granny Bird, grandmother -- Sesame Street
- Dani's Grandma -- A is for Asthma
- Granddaddy Whittiner, The Land of Tinkerdee
- Granny Grouch, grandmother -- Sesame Street Episode 0131
- Grandpa Grouch, grandfather -- Sesame Street Season 15