The character was created by writer Nancy Sans, originally as a day player role. Her first episode, in season 18, involved her getting lost on the way to 123 Sesame Street, where Gordon and two directionally-abled science class students were watching the night sky.
When she was introduced as a regular, she worked at Hooper's Store, getting the job in a 1987 episode. She has developed relationships with Mike and Savion. She was also introduced as one of Gordon's students. During the 1990s, she ran a day care center. Currently, she maintains a veterinary practice in the building that used to serve as a garage in the courtyard between 123 Sesame Street and Hooper's Store. She started studying to be a vet in Season 30, and opened her practice in Season 32. 
Season 46 was the first season since her debut where she did not appear in any new episodes.
She has appeared in the following specials:
- The Sesame Street Special
- Sesame Street: 20 and Still Counting
- Big Bird's Birthday or Let Me Eat Cake
- The Street We Live On
She has also appeared in the following videos:
- The Best of Ernie and Bert
- Big Bird's Favorite Party Games
- Rock & Roll!
- Dance Along!
- Sesame Street Visits the Hospital
- Telling the Truth
- Elmo Visits the Doctor
- What's the Name of That Song?
- Elmo's Potty Time
- Many Friendly Neighbors (2016)