Prüzelius had a long and sucessful career behind him. He graduated from acting school in Göteborg and made his theater debut in 1943. His first of many film credits was the 1946 movie Bra tidning blir bättre, and he became a frequent player in the works of Ingmar Bergman, including films, radio, stage plays, and commercials. He quickly established himself as a desired voice actor due to his distinctive voice as both dubbing actor and as narrator. Some of his voice credits include John F. Kennedy: Years of Lightning, Day of Drums, The Jungle Book as Bagheera, Mulan and many others.