The 4th Sesame Workshop Benefit Gala was held on May 31, 2006.
- Host - Matt Lauer
- Honored - Ann M. Veneman, Executive Director of UNICEF, for her commitment to reducing poverty, malnutrition and disease, and protecting children from abuse and violence, and Alan C. โAceโ Greenberg, Chairman of the Executive Committee of The Bear Stearns Companies Inc., for his work in helping children better cope with trauma and uncertainty.
- Attendees - Lillias White, Michael Bloomberg, Joan Ganz Cooney, Gary Knell
- Muppets - Hoots the Owl, Oscar the Grouch, Zoe, Cookie Monster, Elmo, Ernie, Bert, Grover, Rosita, Telly, Kami (Leslie Carrara-Rudolph)