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Dr. Nose appeared in the "Secret Agents" episode of Bert and Ernie's Great Adventures.
00-Bert and 00-Ernie are sent on a mission to stop the mischievous Dr. Nose from putting fake noses on everyone and everything. They chase him to his hideout on Nose Mountain where they try to unmask Dr. Nose and reveal his true identity.
His name is a spoof of the James Bond villain Dr. No.