Faison also appeared as recurring Sesame Street character Duane (a friend of Jelani's) during the early 90s. He also appeared on City Kids performing the song "Saturday" . His younger brother Olamide Faison plays Miles on Sesame Street.
Faison hosted a PBS special for young adults called Your Life, Your Money, which aired immediately after Sesame Street-based special Families Stand Together: Feeling Secure in Tough Times.
Faison gained notice for the role of Murray in the 1995 film Clueless, and reprised the role for all three seasons on the spin-off television series (1996-1999). Other film credits include Remember the Titans, Josie and the Pussycats, and Uptown Girls. As a voice actor, Faison has been heard on Clone High (as Toots, Martin Luther King Jr., and others) and Robot Chicken.