David Arquette (b. 1971) played Dr. Tucker in Muppets from Space and Daniel in It's a Very Merry Muppet Christmas Movie.
Arquette is one of only five actors to appear on-camera in two feature-length Muppet movies; the others are Jeffrey Tambor, Elliott Gould, Whoopi Goldberg and bit player Dan Payne.
In 2002, he appeared at the unveiling of Kermit the Frog's star on The Hollywood Walk of Fame in a green suit.
He also voices Skully on Disney Channel's Disney Junior series, Jake and the Never Land Pirates.
Arquette as Dr. Tucker with Rizzo
and his fellow rats