AliceThe protagonist of Alice's Adventures in Wonderland; played by Brooke Shields in episode 506

Billie Lee Bonkers attempts to break the jumping-in-place record; played by Sandy Duncan in episode 114.

Billy Lee Boomer a gas station employee played by Jim Nabors in episode 106.

Carl Boomer a heavyweight champion played by Harvey Korman in episode 110.

Lola Bramswell ate seaweed; played by Lena Horne in episode 111.

Clara Cartwell a world traveler and writer; played by Candice Bergen in episode 115.

Inspector Jacques Clouseau Peter Sellers' character from the Pink Panther films, appears briefly in the opening of episode 219

Tiffany Gonzales a hot tempered Hispanic lady, played by Rita Moreno in episode 105.

Gloria Goodbody an expert on physical fitness; played by Ruth Buzzi in episode 104.

Hamletby Christopher Reeve (reluctantly) in episode 418.

Janitor played by Carol Burnett, reprising the role from her television series, in episode 515.

John Denver's Grandma played by John Denver in episode 401.

Mrs. Klinger married to Gus Klinger who turned into a rug; played by Valerie Harper in episode 120.

Emily Litella Gilda Radner's character from Saturday Night Live made a cameo in episode 304.

Lola The Showgirl at the "Copacabana" played by Liza Minnelli in episode 414.

Maid Marian Robin Hood's girlfriend played by Lynn Redgrave in episode 323.

Maurice the Magnificent a ringmaster played by Harvey Korman in episode 110.

Dr. Arnold Nood & Dr. Fredrick Nick two economic professors played by Peter Ustinov and Fozzie in episode 112.

Felix Ogelbaum a Danish doctor who finds a cure for the common cold; played by Peter Ustinov in episode 112.

Gretchen Powers completing the world's longest sentence; played by Kaye Ballard in episode 123.

Robot Politician an invention of Dr. Bunsen Honeydew; played by Peter Ustinov in episode 112.

Scheherezade Storyteller of the 1001 Arabian Nights; played by Marty Feldman in episode 518

Wilbur and Orville Wright played by Marty Feldman in episode 518

Genie of the Lamp an Arabian Nights character; played by Marty Feldman in episode 518

Beverly Shepherd built a pair of wings and flew to Texas (on an airplane); played by Phyllis Diller in episode 118.

Long John Silverstein a pirate invading the Swine Trek; played by John Cleese in episode 223.

Cecilia Sisson an actress from the silent screen with a speech impediment; played by Carol Channing in episode 423.

Luke Skywalker from Star Wars; played by Mark Hamill in episode 417 (but claimed to be his cousin).

Arnold Stockman a retired shoemaker played by Paul Williams in episode 108.

The Swedish Chef's Uncle played by Danny Kaye in episode 316.

Lola Thomas ate a tractor; played by Twiggy in episode 121.

Dr. Kurt Von Frong a practicing psychiatrist played by Peter Ustinov in episode 112.

Charlie McCarthy played by Edgar Bergen in episode 207.

Mortimer Snerd played by Edgar Bergen in episode 207.

The Pied Piper of Hamelinplayed by Jean-Pierre Rampal in episode 510.