Big-Fat-Ugly-Bug-Face-Baby-Eating O'Brien was a deep-voiced, yet beautiful pirate seen in Muppet Treasure Island. She is featured briefly in the crew roll-call.
She is played by Jessica Hamilton who was also a model.
The character was part of the several name gags in the sequence (such as Old Tom, Real Old Tom, and Dead Tom). The nasty name of the beautiful woman was a comic parallel to the beautiful name of the nasty monster Angel Marie, who was next on the roll call. The only difference is that Angel Marie's voice goes with his appearance.
The character is never seen again in the film, neither on the ship nor the island – leaving the audience to wonder what happened to the beautiful Ms. O'Brien after roll was called.