Bobby was arrested in episode 405, and he left the Babies in the care of Miss Piggy, who tried to prove to Kermit that she would make a good mother. The Babies tore up Miss Piggy's dressing room, and drove her crazy. They also performed onstage in that episode, playing Tchaikovsky's Piano Concerto No. 1 with Victor Borge. Bobby returned at the end of the episode to take charge of the Babies again.
The Babies have also made cameo appearances in The Muppet Movie, The Muppets Take Manhattan, The Muppet Christmas Carol and The Muppets. One of them appears in a fantasy sequence in The Muppet Show Comic Book: Family Reunion part 4, under the name "Dimples McSquirt", a master tapioca thief wanted in three continents.
The babies play a featured role in Muppets Most Wanted, where Constantine and Dominic use them to help steal the Crown Jewels. Their performers included Bill Barretta, (the lead), David Rudman, Dave Goelz, Eric Jacobson, Peter Linz, Matt Vogel, Warrick Brownlow-Pike, Andrew Spooner, Olly Taylor, and Andy Heath.
- The Muppet Show
- Episode 308: Loretta Lynn ("One's on the Way")
- Episode 317: Spike Milligan
- Episode 319: Elke Sommer ("Pennsylvania 6-5000")
- Episode 322: Roy Rogers & Dale Evans ("Deep in the Heart of Texas")
- Episode 402: Crystal Gayle ("River Road")
- Episode 405: Victor Borge ("Piano Concerto No. 1")
- Episode 408: Arlo Guthrie
- Episode 503: Joan Baez
- Episode 510: Jean-Pierre Rampal ("Ease on Down the Road")
- Episode 511: Paul Simon ("Baby Driver")
- The Muppet Movie ("Rainbow Connection" Finale)
- The Muppets Take Manhattan (Wedding Finale)
- The Muppet Christmas Carol
- The Muppets
- Muppets Most Wanted
- Jim Henson's Muppet Show Bill
- The Muppet Show Comic Book: Family Reunion Part 2
- The Muppets Character Encyclopedia