"Alphabet Blues" is a Sesame Street song from the video, Do the Alphabet.

Baby Bear sings the song during a meeting of the Sesame Street Alphabet Support Group. The song expresses his frustration in saying the alphabet, because no matter how far he gets through it, he always forgets the rest of the letters and is saddened by the fact that there's many more left. Zoe and Betty Lou sing during the last verse.

Baby Bear later sang the song with Rosie O'Donnell and Whoopi Goldberg during an appearance on The Rosie O'Donnell Show on November 11, 1998.