2001: A Space Odyssey is a science fiction story by Arthur C. Clarke and a movie directed by Stanley Kubrick.
- In episode 211 of Muppets Tonight, Andie MacDowell has requested to play a southern belle on the show. Kermit attempts to oblige, but the Muppets Tonight writers keep getting it wrong. When they finally hand in a suitable script, Kermit lets them touch the monolith. As they go crazy, hitting it with bones, "Also sprach Zarathustra" by Richard Strauss plays, an homage to the film.
- The AL-1995 Plus Tax is a reference to HAL 9000, the computer from the film.